MOUSE THYMUS-INDEPENDENT AND THYMUS-DERIVED LYMPHOID CELLS
نویسندگان
چکیده
منابع مشابه
Mouse Thymus-independent and Thymus-derived Lymphoid Cells
The simultaneous use on mouse lymphoid suspensions of heterologous antisera directed against thymus-derived (T) cell mouse-specific lymphocyte antigen and brain-associated theta antigen (MSLA and BAtheta) or thymus-independent (B) cell mouse-specific bone marrow-derived lymphocyte antigen (MBLA) surface antigens allowed direct proof of the different specificity of these antisera by double immun...
متن کاملSurface Immunoglobulins on Thymus and Thymus-derived Lymphoid Cells
Lymphoid cells from thymus, thoracic duct lymph (TDL), and thoracic duct lymph in irradiated animals reconstituted with allogeneic thymus cells (TTDL) were labeled with radioiodinated anti-immunoglobulins using radioautographic techniques. Thymus and TTDL were labeled (14.4 and 37.0%, respectively) with anti-light chain protein after prolonged exposures (30-60 days). No labeling was observed on...
متن کاملThe thymus and lymphoid proliferation.
I N THIS ISSUE, a review is presented by Arnason, Jankovic and Waksman on some of the functions of the thymus gland, bearing particularly upon its relation to lymphocytes and immune reactions. This gland, long known as an obscure collection of lymphoid or paralymphoid cells, has recently jumped into prominence as possibly the “master gland” controlling the immune response. Jacques Miller,’ work...
متن کاملUnique progenitors in mouse lymph node develop into CD127+ NK cells: thymus-dependent and thymus-independent pathways.
A subset of natural killer (NK) cells in normal mouse lymph node (LN) expresses CD127 (IL-7 receptor-α chain) and is thought to derive from the thymus. However, CD127(+) NK cells are found in the LN of athymic mice. Therefore, the origin of CD127(+) NK cells in the LN is unclear. Here, we have identified unique NK-cell progenitors (NKPs) in the LN that express the pan-NK cell marker CD49b and C...
متن کاملThymus-derived Rosettes Are Not "helper" Cells
Rosettes against SRBC were made from normal spleen cells. Although T rosettes tend to dissociate, they could be stabilized with 0.05% sodium azide. A clear separation of nonrosettes, T rosettes, and B rosettes was obtained by subjecting the suspension of splenic rosettes to velocity sedimentation at unit gravity. Each fraction was injected with either normal bone marrow cells or normal thymus c...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1972
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.136.5.984